To fix windows 64 bit os including prolific usb to serial adapter follow through these steps.
Usb to serial adapter windows 10 compatible.
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Click ok to apply the setting.
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Starting in windows 10 a windows app can send requests to usbser sys by using the windows devices serialcommunication namespace.
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Click the power management tab.
It defines windows runtime classes that can use to communicate with a usb cdc device through a serial port or some abstraction of a serial port.
Right click the first usb root hub device and select properties.
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Follow the prompt by plugging in one usb to serial adapter the click on continue.
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The reason why many usb serial adapters does not work with windows 10 is because these adapters are made with a low cost processor chip which complies only with the minimum requirements or less.
Expand universal serial bus controllers by clicking the arrow to the left of it.
Remove every usb to serial adapter from your pc and double click the pl2303 64bit installer exe.